Tseng YY, Liou JM, Hsu TL, Cheng WC, Wu MS, Wong CH, 2014, “Development of bacterial transglycosylase inhibitors as new antibiotics: moenomycin A treatment for drug-resistant Helicobacter pylori.”, Bioorganic & medicinal chemistry letters, 24(11), 2412-2414. (SCIE)
Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH, 2014, “Enzymatic Synthesis of Lipid II and Analogues.”, Angewandte Chemie-International Edition, 53(31), 8060-8065. (SCIE)
Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH, 2014, “Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition.”, The Journal of organic chemistry, 79(18), 8629-8637. (SCIE)
Hung, Shang-Cheng
Ko YC; Tsai CF; Wang CC; Dhurandhare VM; Hu PL; Su TY; Lico LS; Zulueta MM; Hung SC., 2014, “Microwave-assisted one-pot synthesis of 1,6-anhydrosugars and orthogonally protected thioglycosides.”, J Am Chem Soc., 136, 14425-14431. (SCIE)
Chang CH; Lico LS; Huang TY; Lin SY; Chang CL; Arco SD; Hung SC., 2014, “Synthesis of the heparin-based anticoagulant drug Fondaparinux.”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 9876-9879. (SCIE)
Li YC; Ho IH; Ku CC; Zhong YQ; Hu YP; Chen ZG; Chen CY; Lin WC; Zulueta MM; Hung SC; Lin MG; Wang CC; Hsiao CD., 2014, “Interactions That Influence the Binding of Synthetic Heparan Sulfate Based Disaccharides to Fibroblast Growth Factor-2”, ACS Chem Biol., 9, 1912-1717. (SCIE)
Hsu Y; Ma HH; Lico LS; Jan JT; Fukase K; Uchinashi Y; Zulueta MM; Hung SC., 2014, “One-pot synthesis of N-acetyl- and N-glycolylneuraminic acid capped trisaccharides and evaluation of their influenza A(H1N1) inhibition.”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 2413-2416. (SCIE)
Patil, P. S.; Zulueta, M. M. L.; Hung, S.-C., 2014, “Synthesis of Phosphatidylinositol Mannosides”, Journal of the Chinese Chemical Society, 61, 151-162. (SCIE)
Huang, T.-Y.; Zulueta, M. M. L.; Hung, S.-C., 2014, “Regioselective One-pot Protection, Protection-Glycosylation and Protection- Glycosylation-Glycosylation of Carbohydrates: A Case Study with D-Glucose”, Organic & Biomolecular Chemistry, 12(2), 376-382. (SCIE)
Juan, Li-Jung
Chu CS, Lo PW, Yeh YH, Hsu PH, Peng SH, Teng YC, Kang ML, Wong CH, Juan LJ, 2014, “O-GlcNAcylation regulates EZH2 protein stability and function.”, Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1355-60. (SCIE)
Li, Tsung-Lin
S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Huang, Y. H. Chiu, C. M. Huang, N. S. Hsu, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing vancomycin-resistant Enterococcus”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(31), 10989-10995. (SCIE)
X. W. Zou, Y. C. Liu, N. S. Hsu, C. J. Huang, S. Y. Lyu, H. C. Chan, C. Y. Chang, H. W. Yeh, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Structure and mechanism of a non-heme iron-SAM dependent C-methyltransferase and its engineering to hydratase and O-methyltransferase”, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 70(6), 1549-1560.
K. C. Wang, S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, 2014, “Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple-reaction complexes”, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 70(5), 1401-1410.
C. Y. Chang, S. Y. Lyu, Y. C. Liu, N. S. Hsu, C. C. Wu, C. F. Tang, K. H. Lin, J. Y. Ho, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53(7), 1943-1948. (SCIE)
Liang, Chi-Ming
Ho, M. Y., Hung S. W., Liang, C. M.*, Liang, S. M. , 2014, “Recombinant viral capsid protein VP1 suppresses lung cancer metastasis by inhibiting COX-2/PGE2 and MIG-7 ”, Oncotarget, 5(11), 3931-3943.
Ma, Che Alex
Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY, Lee WH, 2014, “Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-kappaB-mediated antiapoptotic pathway.”, Oncogene, 33, 2968-2977. (SCIE)
Chen PC, Chuang PK, Chen CH, Chan YT, Chen JR, Lin SW, Ma C, Hsu TL, Wong CH, 2014, “Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.”, ACS chemical biology, 9(7), 1437-1443. (SCIE)
Kung CC, Naik MT, Wang SH, Shih HM, Chang CC, Lin LY, Chen CL, Ma C, Chang CF, Huang TH, 2014, “Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.”, The Biochemical journal, 462(1), 53-65. (SCIE)
Chen JR, Yu YH, Tseng YC, Chiang WL, Chiang MF, Ko YA, Chiu YK, Ma HH, Wu CY, Jan JT, Lin KI*, Ma C*, Wong CH*, 2014, “Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections.”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2476-2481. (SCIE)
Wong, Chi-Huey
J -R. Huang , Y.-C. Tsia , Y.-J. Chang , J.-C. Wu , J.-T. Hung , K.-H. Lin , C.-H. Wong and Alice L. Yu, 2014, “alpha-Galactosylceramide but Not Phenyl-Glycolipids Induced NKT Cell Anergy and IL-33-Mediated Myeloid-Derived Suppressor Cell Accumulation via Upregulation of egr2/3.”, Journal of immunology, 192(4), 1972-1981. (SCIE)
J.-J. Shie, Y.-C. Liu, Y.−M. Lee, C. Lim, J.-M. Fang, C.-H. Wong, 2014, “An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation”, Journal of the American Chemical Society, 136(28), 9953-9961. (SCIE)
Chung-Yi Wu, Chi-Huey Wong, 2014, “Automated programmable one-pot synthesis of glycans”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 45-52, Japan: Springer Japan.
Chung-Yi Wu, Chi-Huey Wong, 2014, “Automation in glycan synthesis”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 345-351, Japan: Springer Japan.
E. Falkowska, A. Ramos, K. J. Doores, J. H. Lee, C. Blattner, A. Ramirez, R. Derking, M. J. van Gils, C.-H. Liang, R. Mcbride, S. S. Shivatare, C.-Y. Wu, P.-Y. Chan-Hui, Y. Liu, T. Feizi, M. B. Zwick, W. C. Koff, M. S. Seaman, K. Swiderek, J. P. Moore, J. C. Paulson, C.-H. Wong, A. B. Ward, I. A. Wilson, R. W. Sanders, P. Poignard, and D. R. Burton, 2014, “Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers.”, Immunity, 40(5), 657-668. (SCIE)
A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler , 2014, “Characterization of the sialic Acid binding activity of influenza a viruses using soluble variants of the h7 and h9 hemagglutinins.”, PloS one, 9(2), e89529. (SCIE)
J.-M. Fang, Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, 2014, “Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity.”, Bioorganic & medicinal chemistry, 22(5), 1766-1772. (SCIE)
Chi-Huey Wong, 2014, “Chemo-enzymatic Synthesis of Glycans: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 293-294, Japan: Springer Japan.
Chi-Huey Wong and Naoyuki Taniguchi, 2014, “Current Status and New Challenges”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 11-14, Japan: Springer Japan.
Y.-Y. Tseng, J.-M. Liou, T.-L. Hsu, W.-C. Cheng, M.-S. Wu, C.-H. Wong, 2014, “Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori.”, Bioorganic & medicinal chemistry letters, 24(11), 2412-2414. (SCIE)
L.-Y. Huang, S.-H. Huang, Y.-C. Chang, W.-C. Cheng, T.-J. R. Cheng, and C.-H. Wong, 2014, “Enzymatic Synthesis of Lipid II and Analogues.”, Angewandte Chemie-International Edition, 53(31), 8060-8065. (SCIE)
S.-C. Lin, W.-C. Liu, J.-T. Jan, C.-H. Wong, S.-C. Wu, 2014, “Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses”, PLoS One, 9(3), e92822. (SCIE)
Chi-Huey Wong, 2014, “Homogeneous Glycoproteins: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 959-962, Japan: Springer Japan.
Chung-Yi Wu, Chi-Huey Wong, 2014, “Imaging by Click Chemistry”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 459-465, Japan: Springer Japan.
C.-H. Hsu, M. Schelwies, S. Enck, L.-Y. Huang, S.-H. Huang, Y.-F. Chang, T.-J. Cheng, W.-C. Cheng, C.-H. Wong, 2014, “Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition.”, The Journal of organic chemistry, 79(18), 8629-8637. (SCIE)
H.-Y. Lee, C.-Y. Chen, T.-I. Tsai, S.-T. Li, K.-H. Lin, Y.-Y. Cheng, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, 2014, “Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen”, J. Am. Chem. Soc., 136(48), 16844-16853. (SCIE)
Tsung-I Tsai, Chung-Yi Wu, Chi-Huey Wong, 2014, “Large-scale enzymatic synthesis of glycans with cofactor regeneration”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 409-417, Japan: Springer Japan.
Chi-Huey Wong, 2014, “Molecular Probes for Glycosylation: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 455-457, Japan: Springer Japan.
C.-S. Chu, P.-W. Lo, Y.-H. Yeh, P.-H. Hsu, S.-H. Peng, Y.-C. Teng, M.-L. Kang, C.-H. Wong and L.-J. Juan, 2014, “O-GlcNAcylation regulates EZH2 protein stability and function.”, Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1355-1360. (SCIE)
B.-T. Hong, C.-L. Chen, Jim-Min Fang, Shi-Yun Wang, Wen-I Huang, Yih-Shyun E. Cheng, and Chi-Huey Wong, 2014, “Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives as Influenza Neuraminidase Inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY, 22(23), 6647-6654. (SCIE)
J.-T. Hung, Y.-C. Tsai, W.-D. Lin, J.-T. Jan, K.-H. Lin, J.-R. Huang, J.-Y. Cheng, M.-W. Chen, C.-H. Wong, and A. L. Yu, 2014, “Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus.”, Antiviral research, 107, 110-118. (SCIE)
Chung-Yi Wu, Chi-Huey Wong, 2014, “Preparation of glycan array and its applications”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 35-43, Japan: Springer Japan.
P.-C. Chen, P.-K. Chuang, C.-H. Chen, J.-R. Chen, S.-W. Lin, C. Ma, T.-L. Hsu, C.-H. Wong, 2014, “Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.”, ACS chemical biology, 9(7), 1437-1443. (SCIE)
C.-Y. Wang, C.-Y. Wu, T.-J. Hung, C.-H. Wong, C.-H. Chen, 2014, “Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H.”, Biochemical and biophysical research communications, 452(3), 484-489. (SCIE)
Y.-W. Lou, P.-Y. Wang, S.-C. Yeh, P.-K. Chuang, S.-T. Li, C.-Y. Wu, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, 2014, “Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2482-2487. (SCIE)
C.-L. Chen, T.-C. Lin, S.-Y. Wang, J.-J. Shie, K.-C. Tsai, Y.-S. E. Cheng, J.-T. Jan, C.-J. Lin, J.-M. Fang, and C.-H. Wong, 2014, “Tamiphosphor Monoesters as Effective Anti-influenza Agents”, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 81, 106-118. (SCIE)
J. Lin, Y.-J. Chang, W.-B. Yang, A. L. Yu, and C.-H. Wong, 2014, “The Multifaceted Effects of Polysaccharides Isolated from Dendrobium huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes.”, PloS one, 9(4), e94040. (SCIE)
J.-R. Chen, Y.-H. Yu, Y.-C. Tseng, W.-L. Chiang, M.-F. Chiang, Y.-A. Ko, Y.-K. Chiu, S.-H. Ma, C.-Y. Wu, J.-T. Jan, K.-I. Lin, C. Ma and C.-H. Wong, 2014, “Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2476-2481. (SCIE)
Chung-Yi Wu, Chi-Huey Wong, 2014, “Vaccines”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 1529-1508, Japan: Springer Japan.
Wu, Chung-Yi
Lee, H.-Y., Chen, C.-Y., Tsai, T.-I., Li, S.-T., Lin, K.-H., Cheng, Y.-Y., Ren, C.-T., Cheng, T.-J., Wu, C.-Y.*, Wong, C.-H.* , 2014, “Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, 16844-16853. (SCIE)
Wu, C.-S., Lee, T.-Y., Chou, R.-H., Yen, C.-J., Huang, W.-C., Wu, C.-Y., Yu, Y.-L., 2014, “Development of a Highly Sensitive Glycan Microarray for Quantifying AFP-L3 for Early Prediction of Hepatitis B Virus-Related Hepatocellular Carcinoma.”, PLoS One, 9, e99959. (SCIE)
Wang, C.-Y., Wu, C.-Y., Hung, T.-J., Wong, C.-H., Chen, C.-H.* , 2014, “Sequence-Constructive SELEX: A New Strategy for Screening DNA Aptamer Binding to Globo H”, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 452, 484-489. (SCIE)
Chen-Shiou Wu, Chia-Jui Yen, Ruey-Hwang Chou, Chung-Yi Wu*, Yung-Luen Yu*, 2014, “Downregulation of MicroRNA-15b by Hepatitis B Virus X Enhances Hepatocellular Carcinoma Proliferation via Fucosyltransferase 2-Induced Globo H Expression”, INTERNATIONAL JOURNAL OF CANCER, 134(7), 1638-1647. (SCIE)
Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R Cheng, C.-Y. Wu,* J.-M. Fang,*C.-H. Wong*, 2014, “Chemical Constituents of Plectranthus amboinicus and the Synthetic Analogs Possessing Anti-inflammatory Activity”, BIOORGANIC & MEDICINAL CHEMISTRY, 22(5), 1766-1772. (SCIE)
A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels,C.-Y. Wu, C.-H., 2014, “Characterization of the Sialic Acid Binding Activity of Influenza A Viruses Using Soluble Variants of the H7 and H9 Hemagglutinins”, PLoS One, 9(2), e89529. (SCIE)
Lou,Y.-W., Wang, P.-Y., Yeh, S.-C., Chuang, P.-K., Li, S.-T., Wu, C.-Y., Khoo, K.-H., Hsiao, M., Hsu, T.-L., Wong, C.-H.* , 2014, “Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111, 2482-2487. (SCIE)
Juine-Ruey Che, 2014, “Vaccination of Monoglycosylated Hemagglutinin Induces Cross-Strain Protection against Influenza Virus Infections”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(7), 2476-2481. (SCIE)
Yang, An-Suei
Hung-Pin Peng, Kuo Hao Lee, Jhih-Wei Jian, An-Suei Yang*, 2014, “Origins of specificity and affinity in antibody-protein interactions”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(26), E2656-E2665. (SCIE)
Rajasekaran Mahalingama*, Hung-Pin Peng, An-Suei Yang*, 2014, “Prediction of fatty acid-binding residues on protein surfaces with three-dimensional probability distributions of interacting atoms”, BIOPHYSICAL CHEMISTRY, 192, 10-19. (SCIE)
Rajasekaran Mahalingam*, Hung-Pin Peng, An-Suei Yang*, 2014, “Prediction of FMN-binding residues with three-dimensional probability distributions of interacting atoms on protein surfaces”, JOURNAL OF THEORETICAL BIOLOGY, 343, 154-161. (SCIE)
Hsu, H.-J., K. H. Lee, J.-W. Jian, H.-J. Chang, C.-M. Yu, Y.-C. Lee, I.-C. Chen, H.-P. Peng, C. Y. Wu, Y.-F. Huang, C.-Y. Shao, K. P. Chiu and A.-S. Yang*, 2014, “Antibody variable domain interface and framework sequence requirements for stability and function by high throughput experiments.”, STRUCTURE, 22(1), 22-34. (SCIE)
Chang, H.-J., J.-W. Jian, H.-J. Hsu, Y.-C. Lee, H.-S. Chen, J.-J. You, S.-C. Hou, C.-Y. Shao, Y.-J. Chen, K.-P. Chiu, H.-P. Peng, K. H. Lee and A.-S. Yang*, 2014, “Loop sequence features and stability determinants in antibody variable domains by high throughput experiments.”, STRUCTURE, 22(1), 9-21. (SCIE)
Chang, H.-J. and A.-S. Yang*, 2014, “Design of Phage-Displayed Cystine-Stabilized Mini-Protein Libraries for Proteinaceous Binder Engineering”, Methods in Molecular Biology, 1088, 1-17.
Hsu, H.-J. and A.-S. Yang*, 2014, “Substrate Phage Display for Protease Substrate Sequence Characterization: Bovine Factor Xa as a Model System”, Methods in Molecular Biology, 1088, 107-124.